faculty Profile

• B.Tech. (Biotechnology), Anna University Chennai, 2010.
• M.Tech. (Biotechnology), Anna University Chennai, 2012.
• Ph.D.(Biochemistry and Molecular Biology), Madras University, Chennai, 2022.

Teaching

• Assistant Professor, Sri Venkateswara College of Engineering,Sriperumbudur, Tamil Nadu (August 2022 – till date)

Theory Courses

• Molecular Biology
• Immunology
• Biology for Engineers
• Fluid Mechanics and Heat Transfer

Laboratory Courses

• Immunology Laboratory
• Instrumentation Method of Analysis Laboratory

Patents
• Name of the Student: Ms. S. Kamali and Ms. S.S. Dhakshini
• Name of the Faculty Mentor: Dr. J.Isaivani
• Title of the Project: Garlic Encapsulated Chitosan Nanoparticles for the Treatment of High Glucose Induced Renal Cell Fibrosis
• Name of the Funding Agency: Intramural Research grant
• Sanctioned Amount: Rs. 10,000/-
• Duration: 2023-2024
• Status: Completed

Research papers:

• Sundararajan S, Jayachandran I, Pandey G K, Venkatesan U, Rajagopal A, Gokulakrishnan K, Balasubramanyam M, Mohan V, ‘Manickam N (2023) Metformin Reduces the Progression of Atherogenesis by Regulating the Sestrin2-mTOR Pathway in Obese and Diabetic Rats’, Journal of Lipid and Atherosclerosis, Vol.12 (3), pp. 290-306.
• Jayachandran I, Sundararajan S, Venkatesan S, Paadukaana S, Balasubramanyam M, Mohan V, & Manickam N. (2020), ‘Asymmetric dimethylarginine (ADMA) accelerates renal cell fibrosis under high glucose condition through NOX4/ROS/ERK signaling pathway’, Scientific reports, Vol.10(1), pp.1-17.
• Sundararajan S, Jayachandran I, Subramanian S C, Anjana R M, Balasubramanyam M, Mohan V, Venkatesan B, & Manickam N (2021), ‘Decreased Sestrin levels in patients with type 2 diabetes and dyslipidemia and their association with the severity of atherogenic index’, Journal of endocrinological investigation, Vol. 44(7), pp.1395-1405.
• Sundararajan S, Jayachandran I, Balasubramanyam M, Mohan V, Venkatesan B, & Manickam N (2018), ‘Sestrin2 regulates monocyte activation through AMPK-mTOR nexus under high-glucose and dyslipidemic conditions’, Journal of cellular biochemistry, Vol.120(5), pp.8201-8213
• Jayachandran I, Sundararajan S, Paramasivam P, Venkatesan B, Subramanian S C, Balasubramanyam M, Mohan V, & Manickam N (2017), ‘Association of circulatory asymmetric dimethylarginine (ADMA) with diabetic nephropathy in Asian Indians and its causative role in renal cell injury’, Clinical biochemistry, Vol. 50(15), pp. 835-842.

Conferences Attended:

• “Asymmetric Dimethylarginine and 20-Hydroxyeicosatetraenoic Acid-A lethal combo in diabetic kidney disease”, International Diabetes Federation congress, Virtual, 6/11/2021to 11/11/2021.
• “Aegle marmelos ameliorates high glucose induced renal cell fibrosis by down regulating NOX4 induced ROS generation: Involvement of gasotransmitters”, 88th Annual Meeting of SBCI and conference on Advances at the interface of biology and chemistry (SBCI), Bhabha Atomic Research Centre (BARC), Mumbai, Maharashtra, 31/10/2019 to 3/11/2019.
• “Asymmetric dimethylarginine (ADMA) accelerates renal cell fibrosis by activating NOX4/ROS/ERK signalling”, Indian Science Congress, Lovely Professional University, Phagwara, Jalandhar, Punjab, 3/01/2019 to 07/01/2019.
• “Metformin, an activator of AMPK, impedes the progression of atherosclerosis by regulating sestrin2-mTOR pathway”, Indian Science Congress, Lovely Professional University, Phagwara, Jalandhar, Punjab, 3/01/2019 to 07/01/2019.
• “Asymmetric dimethylarginine (ADMA): A potential early biomarker for diabetic nephropathy”, 42nd Annual conclave of Research Society for Study of Diabetes in India (RSSDI), Bangalore, Karnataka, 21/11/2014 to 23/11/2014.
• “Study of immune response to cervical cancer vaccine GARDASIL in Tuberculosis Patients”, International Conference on Exploration of Biotechnology by Student Scholars and Research, Shridevi Institute of Engineering and Technology, Tumkur, Karnataka, 08/06/2012 to 09/06/2012.

Workshop Organised:
• National Workshop on Design of Experiments and Ethics in Preclinical Research, Sri Venkateswara College of Engineering, Sriperumbudur, 17/10/2023, Coordinator.

FDP Attended:

• 5-day Online Universal Human Values FDP, Organized by AICTE, Online, 3/07/2023to 7/07/2023.

Current Responsibilities
• Consumables and non-consumables in-charge
• PALS/VLAB coordinator
• Bio-Organic Chemistry laboratory in-charge
• Library In-charge

Previous Responsibilities

• Faculty Advisor (Batch 2020-2024)
• Department Meetings Minutes In-charge
• Assistant CAT coordinator
• Assistant ISO coordinator

• State Level Eligibility Test for Lectureship, (SLET), Government of Tamilnadu, 2012.
• Junior Research Fellowship, Department of Science and Technology (DST), 2013.
• Senior Research Fellowship, Council of Scientific and Industrial Research (CSIR,) 2017.