Profile
Name Dr. Isaivani. J
Designation Assistant Professor
Areas of Interest Molecular Biology
Room No.
Intercom No.
Mobile 9597139461
Email Id (Official) isaivanij@svce.ac.in
Email Id (Personal) isai.isaijai@gmail.com
Qualification
  • B.Tech. (Biotechnology), Anna University Chennai, 2010.
  • M.Tech. (Biotechnology), Anna University Chennai, 2012.
  • Ph.D.(Biochemistry and Molecular Biology), Madras University, Chennai, 2022.
Academic Experience
Courses Handled
Research & Consultancy
    Research

  • Research Scholar, Madras Diabetes Research Foundation, SIPCOT-IT park, Siruseri, Chennai, Tamil Nadu (February, 2020 – January, 2021)
  • Senior Research Fellow, Madras Diabetes Research Foundation, SIPCOT-IT park, Siruseri, Chennai, Tamil Nadu (September, 2017- January, 2020)
  • Junior Research Fellow, Madras Diabetes Research Foundation, SIPCOT-IT park, Siruseri, Chennai Tamil Nadu (August, 2013 -January, 2017)

    • Research papers:

  • Jayachandran I, Sundararajan S, Venkatesan S, Paadukaana S, Balasubramanyam M, Mohan V, & Manickam N. (2020), ‘Asymmetric dimethylarginine (ADMA) accelerates renal cell fibrosis under high glucose condition through NOX4/ROS/ERK signaling pathway’, Scientific reports, Vol.10(1), pp.1-17.
  • Sundararajan S, Jayachandran I, Subramanian S C, Anjana R M, Balasubramanyam M, Mohan V, Venkatesan B, & Manickam N (2021), ‘Decreased Sestrin levels in patients with type 2 diabetes and dyslipidemia and their association with the severity of atherogenic index’, Journal of endocrinological investigation, Vol. 44(7), pp.1395-1405.
  • Sundararajan S, Jayachandran I, Balasubramanyam M, Mohan V, Venkatesan B, & Manickam N (2018), ‘Sestrin2 regulates monocyte activation through AMPK-mTOR nexus under high-glucose and dyslipidemic conditions’, Journal of cellular biochemistry, Vol.120(5), pp.8201-8213
  • Jayachandran I, Sundararajan S, Paramasivam P, Venkatesan B, Subramanian S C, Balasubramanyam M, Mohan V, & Manickam N (2017), ‘Association of circulatory asymmetric dimethylarginine (ADMA) with diabetic nephropathy in Asian Indians and its causative role in renal cell injury’, Clinical biochemistry, Vol. 50(15), pp. 835-842.

    • Conferences Attended:

  • “Asymmetric Dimethylarginine and 20-Hydroxyeicosatetraenoic Acid-A lethal combo in diabetic kidney disease”, International Diabetes Federation congress, Virtual, 6/11/2021to 11/11/2021.
  • “Aegle marmelos ameliorates high glucose induced renal cell fibrosis by down regulating NOX4 induced ROS generation: Involvement of gasotransmitters”, 88th Annual Meeting of SBCI and conference on Advances at the interface of biology and chemistry (SBCI), Bhabha Atomic Research Centre (BARC), Mumbai, Maharashtra, 31/10/2019 to 3/11/2019.
  • “Asymmetric dimethylarginine (ADMA) accelerates renal cell fibrosis by activating NOX4/ROS/ERK signalling”, Indian Science Congress, Lovely Professional University, Phagwara, Jalandhar, Punjab, 3/01/2019 to 07/01/2019.
  • “Metformin, an activator of AMPK, impedes the progression of atherosclerosis by regulating sestrin2-mTOR pathway”, Indian Science Congress, Lovely Professional University, Phagwara, Jalandhar, Punjab, 3/01/2019 to 07/01/2019.
  • “Asymmetric dimethylarginine (ADMA): A potential early biomarker for diabetic nephropathy”, 42nd Annual conclave of Research Society for Study of Diabetes in India (RSSDI), Bangalore, Karnataka, 21/11/2014 to 23/11/2014.
  • “Study of immune response to cervical cancer vaccine GARDASIL in Tuberculosis Patients”, International Conference on Exploration of Biotechnology by Student Scholars and Research, Shridevi Institute of Engineering and Technology, Tumkur, Karnataka, 08/06/2012 to 09/06/2012.
Conference / Workshop / FDP
Laboratory Handled
Training Attended
Additional Responsibilities
  • Faculty Advisor for B. Tech III Year
  • PALS/VLAB Coordinator
  • Department Meeting Minutes in-charge
  • Assistant CAT Coordinator
  • Assistant ISO Coordinator
Achievements
  • State Level Eligibility Test for Lectureship, (SLET), Government of Tamilnadu, 2012.
  • Junior Research Fellowship, Department of Science and Technology (DST), 2013.
  • Senior Research Fellowship, Council of Scientific and Industrial Research (CSIR,) 2017.
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